Gene transfer, speciation, and the evolution of bacterial genomes

Curr Opin Microbiol. 1999 Oct;2(5):519-23. doi: 10.1016/s1369-5274(99)00010-7.


Studies in microbial evolution have focused on the origin and vertical transmission of genetic variation within populations experiencing limited recombination. Genomic analyses have highlighted the importance of horizontal genetic transfer in shaping the composition of microbial genomes, providing novel metabolic capabilities, and catalyzing the diversification of bacterial lineages.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / genetics*
  • Conjugation, Genetic*
  • Evolution, Molecular*
  • Gene Transfer, Horizontal
  • Genes, Bacterial
  • Genetic Variation
  • Genome, Bacterial*
  • Mutation
  • Species Specificity
  • Transduction, Genetic*
  • Transformation, Bacterial*