[Description of palpebral involvement in Fraser's syndrome]

J Fr Ophtalmol. Aug-Sep 1999;22(7):755-9.
[Article in French]

Abstract

Goal: Fraser's syndrome is a rare multiple malformation involving the eyes, with cryptophthalmos. In its complete form, cryptophthalmos is a serious malformation with absence of eyelids and palpebral fissure. A review of ophthalmological signs is presented.

Case report: A case of Fraser's syndrome is presented. Ophthalmological and somatic examination as well as evolution are described.

Results: Incomplete cryptophthalmos with symblepharon and bilateral palpebral coloboma are present. Surgical treatment with palpebral reconstruction allowed preservation of visual acuity in one eye.

Discussion: Ophthalmological signs are present in 93% of cases. Eyelid involvement such as symblepharon, and partial or complete coloboma are relatively frequent, whereas cryptophthalmos in its complete form are much more rare.

Conclusion: Treatment involves palpebral reconstructive surgery in order to preserve visual function.

Publication types

  • Case Reports
  • Comparative Study
  • English Abstract

MeSH terms

  • Abnormalities, Multiple* / diagnosis
  • Coloboma* / diagnosis
  • Eye Abnormalities* / diagnosis
  • Eye Abnormalities* / surgery
  • Eyelids / abnormalities*
  • Eyelids / surgery
  • Female
  • Humans
  • Infant, Newborn
  • Prognosis
  • Syndrome
  • Visual Acuity