Synthesis and antimicrobial activity of some new benzimidazole carboxylates and carboxamides

G Ayhan-Kilcigil; M Tunçbilek; N Altanlar; H Göker

doi:10.1016/s0014-827x(99)00059-2

Synthesis and antimicrobial activity of some new benzimidazole carboxylates and carboxamides

Farmaco. 1999 Aug 30;54(8):562-5. doi: 10.1016/s0014-827x(99)00059-2.

Authors

G Ayhan-Kilcigil¹, M Tunçbilek, N Altanlar, H Göker

Affiliation

¹ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Tandogan, Turkey.

PMID: 10510853
DOI: 10.1016/s0014-827x(99)00059-2

Abstract

Some benzimidazole carboxylates and carboxamides were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Among the investigated compounds 2d exhibited best activity against C. albicans.

MeSH terms

Amides / chemical synthesis*
Amides / pharmacology
Anti-Bacterial Agents
Anti-Infective Agents / chemical synthesis*
Anti-Infective Agents / pharmacology
Bacteria / drug effects*
Benzimidazoles / chemical synthesis*
Benzimidazoles / pharmacology
Candida albicans / drug effects
Carboxylic Acids / chemical synthesis*
Carboxylic Acids / pharmacology
Chemical Phenomena
Chemistry, Physical
Escherichia coli / drug effects
Fungi / drug effects*
Microbial Sensitivity Tests
Staphylococcus aureus / drug effects

Substances

Amides
Anti-Bacterial Agents
Anti-Infective Agents
Benzimidazoles
Carboxylic Acids