Purpose: To report a case of oligodendroglioma originating from the accessory glia of retina.
Method: Case report of a 72-year-old woman with a tumor in the temporal fundus of the right eye that was suspected to be choroidal melanoma. Enucleation was declined, but 5 years later, because of tumor growth, pain, and loss of light perception, the globe was enucleated.
Results: Histopathologic examination disclosed a neuroepithelial tumor with a structure of oligodendroglioma. Melanoma and metastatic tumor were excluded.
Conclusions: Oligodendrogliomas are rare in the retina but may originate from retinal oligodendrocytes. This case suggests that the differential diagnosis of choroidal melanoma should include the possibility of oligodendroglioma.