Abstract
This patient illustrates a classical case of what many pediatricians call the diphenylhydantoin teratogenic syndrome. It suggests the possibility of an additional ocular finding of retinoschisis and optic nerve abnormalities which could conceivably have a teratogenic basis. The effects of epilepsy and diphenylhydantoin on these formations is discussed.
MeSH terms
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Abnormalities, Drug-Induced / etiology*
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Blepharoptosis / chemically induced
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Child
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Child, Preschool
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Epilepsy / drug therapy
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Eye Abnormalities*
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Female
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Fingers / abnormalities
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Hair / abnormalities
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Humans
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Hypertelorism / chemically induced
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Infant
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Infant, Newborn
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Male
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Optic Nerve / abnormalities
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Phenytoin / adverse effects*
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Phenytoin / therapeutic use
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Pregnancy
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Retinal Detachment / chemically induced
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Strabismus / chemically induced
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Toes / abnormalities