Identification of new early markers of the hypersensitive response in Arabidopsis thaliana(1)

FEBS Lett. 1999 Oct 8;459(2):149-53. doi: 10.1016/s0014-5793(99)01233-8.


New molecular markers of the hypersensitive response (HR) of Arabidopsis thaliana to the bacterial pathogen Xanthomonas campestris pv. campestris (X.c.c.) have been identified by differential screening of a cDNA library constructed from suspension cells inoculated by an HR-inducing strain in the presence of cycloheximide. Seven families of genes (called Athsr) have been isolated, show similarities to voltage-dependent anion channels (VDAC) and alternative oxidases, or are novel proteins. Athsr genes have shown to be specifically or preferentially expressed during the HR. These data suggest that Athsr genes might be involved in early events conditioning the establishment of the HR.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / drug effects
  • Arabidopsis / genetics*
  • Arabidopsis / metabolism
  • Arabidopsis / microbiology
  • Arabidopsis Proteins*
  • Base Sequence
  • Biomarkers
  • Cycloheximide / pharmacology
  • DNA, Complementary / analysis
  • DNA, Plant
  • Genes, Plant
  • Molecular Sequence Data
  • Plant Diseases* / genetics
  • Plant Proteins / genetics*
  • Plant Proteins / metabolism
  • Sequence Homology, Amino Acid
  • Xanthomonas campestris / physiology


  • Arabidopsis Proteins
  • Biomarkers
  • DNA, Complementary
  • DNA, Plant
  • Plant Proteins
  • athsr2 protein, Arabidopsis
  • Cycloheximide

Associated data

  • GENBANK/AJ131391
  • GENBANK/AJ131392
  • GENBANK/AJ243377
  • GENBANK/AJ243378
  • GENBANK/AJ243379
  • GENBANK/AJ243380