Cardiac output and ductal reopening during phototherapy in preterm infants

Acta Paediatr. 1999 Sep;88(9):1014-9. doi: 10.1080/08035259950168540.


Left ventricular output (LVO), left pulmonary artery blood flow (LPA) and patency of the ductus arteriosus (PDA) were studied with 2D/pulsed Doppler ultrasound before, during and after phototherapy treatment in 27 preterm infants (gestational age < or =32 wk), who were exposed for a minimum of 12 h to phototherapy for non-haemolytic hyperbilirubinemia. In 14 infants (52%) the ductus arteriosus reopened during phototherapy, but ductal patency was not of haemodynamic importance. LVO initially decreased in preterm infants in whom the ductus did not reopen. From 12 h until discontinuation of phototherapy, LVO and LPA were higher than before phototherapy in all infants. After withdrawal of phototherapy, LVO and LPA returned to pre-phototherapy values.

MeSH terms

  • Analysis of Variance
  • Birth Weight
  • Blood Flow Velocity
  • Blood Pressure
  • Cardiac Output*
  • Cardiac Output, Low / etiology
  • Ductus Arteriosus, Patent / etiology*
  • Gestational Age
  • Heart Rate
  • Humans
  • Hyperbilirubinemia / therapy*
  • Infant, Newborn
  • Infant, Premature*
  • Phototherapy / adverse effects*
  • Recurrence