Primary appendiceal adenocarcinoma

Am J Clin Oncol. 1999 Oct;22(5):458-9. doi: 10.1097/00000421-199910000-00007.


Adenocarcinoma of the appendix is rarely encountered and is usually discovered at the pathology examination of the surgical specimen. Adenocarcinoma of the vermiform appendix is a rare neoplasm and constitutes <0.5% of all gastrointestinal neoplasms. There is no symptom of appendiceal cancer, and it is very difficult to diagnose preoperatively. Most female patients are diagnosed as having a gynecologic disease. Second primary synchronous and metachronous neoplasms, especially in the gastrointestinal tract, are found in up to 35% of patients with appendix adenocarcinoma. We report a case of adenocarcinoma in a 56-year-old woman misdiagnosed as having right ovarian carcinoma, and we review the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Appendiceal Neoplasms / epidemiology
  • Appendiceal Neoplasms / pathology*
  • Appendiceal Neoplasms / surgery
  • Carcinoma, Signet Ring Cell / epidemiology
  • Carcinoma, Signet Ring Cell / pathology*
  • Carcinoma, Signet Ring Cell / surgery
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms, Second Primary / diagnosis
  • Ovarian Neoplasms / diagnosis
  • Survival Rate