Laryngeal atresia presenting as fetal ascites, olygohydramnios and lung appearance mimicking cystic adenomatoid malformation in a 25-week-old fetus with Fraser syndrome

Prenat Diagn. 1999 Sep;19(9):856-58. doi: 10.1002/(sici)1097-0223(199909)19:9<856::aid-pd628>;2-x.


We describe a 25-week-old female fetus of consanguineous parents with ultrasonographic findings of increased echogenicity of lungs mimicking CAM (cystic adenomatoid malformation) type III, olygohydramnios and fetal ascites. A therapeutic abortion was performed and unilateral cryptophthalmos, laryngeal atresia and bilateral syndactyly of the hands and feet were observed at post-mortem. These findings confirmed the diagnosis of Fraser syndrome after abortion.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / diagnostic imaging*
  • Ascites / etiology*
  • Cystic Adenomatoid Malformation of Lung, Congenital / diagnostic imaging*
  • Diagnosis, Differential
  • Eye Abnormalities / diagnostic imaging
  • Female
  • Fetal Diseases / diagnostic imaging*
  • Gestational Age
  • Humans
  • Larynx / abnormalities*
  • Oligohydramnios / diagnostic imaging*
  • Syndactyly / diagnostic imaging
  • Syndrome
  • Ultrasonography, Prenatal