Treatment of grade 3 anal intraepithelial neoplasia by complete anal mucosal excision without fecal diversion: report of a case

Dis Colon Rectum. 1999 Oct;42(10):1342-4. doi: 10.1007/BF02234227.


Purpose: The aim of this study was to remove completely the risk of malignant transformation without permanent or temporary fecal diversion in a patient with extensive anal intraepithelial neoplasia.

Methods: All anal canal mucosa and the lowest 1.5 cm of rectal mucosa were excised and the adjacent rectal mucosa and submucosa advanced to the anal verge skin.

Results: The patient achieved normal continence within a month after the operation. Multiple anal canal biopsies at 12 months after the operation revealed normal rectal mucosa.

Conclusions: Total anal mucosal excision offers a relatively simple means of removing the malignant risk of anal intraepithelial neoplasia without fecal diversion in selected patients.

Publication types

  • Case Reports

MeSH terms

  • Anus Neoplasms / surgery*
  • Carcinoma in Situ / surgery*
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Intestinal Mucosa / surgery
  • Middle Aged
  • Time Factors