Hepatic sarcoidosis responding to chloroquine as steroid-sparing drug

Indian J Gastroenterol. 1999 Oct-Nov;18(4):177-8.

Abstract

We report a 59-year-old lady who presented with exertional dyspnea and was diagnosed to have sarcoidosis. She responded to steroids, but one year later developed abdominal symptoms and was found to have hepatosplenomegaly. Liver biopsy showed non caseating granulomas. As she had developed steroid-induced diabetes she was started on chloroquine and responded well with regression of the liver and spleen during one year of treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Chloroquine / therapeutic use*
  • Female
  • Humans
  • Liver / pathology
  • Liver Diseases / drug therapy*
  • Liver Diseases / pathology
  • Middle Aged
  • Prednisolone / therapeutic use
  • Sarcoidosis / drug therapy*
  • Sarcoidosis / pathology

Substances

  • Anti-Inflammatory Agents
  • Chloroquine
  • Prednisolone