Role of sinus wall compliance in aortic leaflet function

Am J Cardiol. 1999 Oct 15;84(8):944-6, A7. doi: 10.1016/s0002-9149(99)00475-0.


Functional morphology of the normal aortic root was studied in vitro using 500 frames/s cinematography. Stiffening of the aortic wall by spraying its exterior with plastic adhesive led to compromised function of the leaflets, a phenomenon that may play a role in valve degeneration as it occurs in old-age fibrosis, atherosclerosis, or in connection with certain surgical procedures.

MeSH terms

  • Aortic Valve / anatomy & histology
  • Aortic Valve / physiology*
  • Hemodynamics
  • Humans
  • In Vitro Techniques
  • Video Recording