Successful treatment of Kimura's disease with cyclosporine

J Am Acad Dermatol. 1999 Nov;41(5 Pt 2):893-4. doi: 10.1016/s0190-9622(99)70354-3.


We report the case of a 29-year-old Japanese woman presenting with recurring Kimura's disease. We began treatment with cyclosporine within 7 days, the nodular lesion had almost cleared. The cyclosporine dose was then gradually reduced and discontinued after 6 months. The patient was reassessed 18 months after the cessation of treatment and there was no evidence of recurrence of the disease. We speculate that the effects of cyclosporine on T helper-2 cells improves Kimura's disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Angiolymphoid Hyperplasia with Eosinophilia / drug therapy*
  • Angiolymphoid Hyperplasia with Eosinophilia / pathology
  • Cyclosporine / therapeutic use*
  • Dermatologic Agents / therapeutic use*
  • Ear Diseases / drug therapy*
  • Ear Diseases / pathology
  • Ear, External
  • Female
  • Humans


  • Dermatologic Agents
  • Cyclosporine