Suppression of lactation by an antiestrogen, tamoxifen

Eur J Obstet Gynecol Reprod Biol. 1975;4(5):167-9. doi: 10.1016/0028-2243(75)90022-2.


The efficacy of a new antiestrogen, tamoxifen, in the suppression of lactation was tested in a placebo-controlled double-blind trial in 150 puerperal women. It proved to be very effective in preventing milk secretion and breast engorgement when its administration was commenced within two hours after delivery. No side effects were observed. Two dosage schedules were compared.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Double-Blind Method
  • Female
  • Humans
  • Lactation / drug effects*
  • Postpartum Period
  • Pregnancy
  • Tamoxifen / administration & dosage
  • Tamoxifen / pharmacology*


  • Tamoxifen