Clinical applications of optical coherence tomography

Curr Opin Ophthalmol. 1999 Jun;10(3):182-8. doi: 10.1097/00055735-199906000-00006.


Optical coherence tomography is a new diagnostic tool for high-resolution imaging of ocular tissues. Ocular coherence tomography produces cross-sectional images of the retina with a longitudinal resolution of 10 microns. This provides the most highly resolved retinal images in vivo when compared with other available techniques. It has been used to study the anatomy and pathogenesis of various ocular disorders affecting the posterior segment. These include vitreomacular traction syndrome, macular hole, retinoschisis, macular edema, central serous chorioretinopathy, subretinal neovascularization, age-related maculopathy, optic nerve disorders, and nerve fiber layer evaluation in glaucoma.

Publication types

  • Review

MeSH terms

  • Diagnostic Techniques, Ophthalmological*
  • Humans
  • Image Processing, Computer-Assisted
  • Optics and Photonics
  • Reproducibility of Results
  • Retina / pathology
  • Retinal Diseases / diagnosis
  • Sensitivity and Specificity
  • Tomography / methods*