[Nicotinic acid and nicotinamide]

Nihon Rinsho. 1999 Oct;57(10):2211-7.
[Article in Japanese]

Abstract

Nicotinic acid and nicotinamide are called niacin. They are the antipellagra vitamin essential to many animals for growth and health. In human being, niacin is believed necessary together with other vitamins for the prevention and cure of pellagra. Niacin is widely distributed in nature; appreciable amounts are found in liver, fish, yeast and cereal grains. Nicotinamide is a precursor of the coenzyme NAD and NADP. Some of the most understood metabolic processes that involve niacin are glycolysis, fatty acid synthesis and respiration. Niacin is also related to the following diseases: Hartnup disease; blue diaper syndrome; tryptophanuria; hydroxykynureninuria; xanthurenic aciduria; Huntington's disease.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Humans
  • Niacin / chemistry
  • Niacin / metabolism
  • Niacin / physiology*
  • Niacinamide / chemistry
  • Niacinamide / metabolism
  • Niacinamide / physiology*

Substances

  • Niacinamide
  • Niacin