Normal variants, artefacts and interpretative pitfalls in PET imaging with 18-fluoro-2-deoxyglucose and carbon-11 methionine

Eur J Nucl Med. 1999 Oct;26(10):1363-78. doi: 10.1007/s002590050597.


Interpretation of studies from all imaging modalities requires a knowledge of the possible pitfalls that may occur due to normal variation, artefacts and processes which may mimic pathology. The applications and use of not only 18-fluoro-2-deoxyglucose but also l-[methyl-(11)C] methionine positron emission tomography (PET) are widening and it is timely that the currently recognised interpretative pitfalls are reviewed as the number of dedicated PET scanners and coincidence gamma cameras increases.

Publication types

  • Review

MeSH terms

  • Animals
  • Artifacts
  • Carbon Radioisotopes
  • Fluorodeoxyglucose F18*
  • Humans
  • Methionine*
  • Radiopharmaceuticals*
  • Reference Values
  • Tomography, Emission-Computed


  • Carbon Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • carbon-11 methionine
  • Methionine