Computed tomography and magnetic resonance imaging features of olfactory neuroblastoma: an analysis of 22 cases

Clin Otolaryngol Allied Sci. 1999 Sep;24(5):457-61. doi: 10.1046/j.1365-2273.1999.00295.x.


The computed tomography (CT) and magnetic resonance imaging (MRI) studies of 22 patients with a histologically proven olfactory neuroblastoma were retrospectively reviewed. The tumours displayed a variety of imaging characteristics and aggressiveness. The expansile tendency of olfactory neuroblastoma is characterised by bowing of the sinus walls. The destructive aspect is manifested as tumour replacing the turbinates, septum, and sinus walls with extension into contiguous areas. The density/signal and enhancement characteristics are non-specific. Olfactory neuroblastoma should be suspected in all ages following identification of a mass in the superior nasal cavity demonstrating both expansile and destructive growth patterns. The otorhinolaryngologist and the radiologist should be aware of this tumour entity, as early diagnosis appropriately guides therapy and predicts survival.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Esthesioneuroblastoma, Olfactory / diagnosis*
  • Esthesioneuroblastoma, Olfactory / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Nasal Cavity / diagnostic imaging*
  • Nasal Cavity / pathology*
  • Nose Neoplasms / diagnosis*
  • Nose Neoplasms / surgery
  • Retrospective Studies
  • Tomography, X-Ray Computed