Transplantation tolerance-where do we stand?

Nat Med. 1999 Nov;5(11):1245-8. doi: 10.1038/15197.


Our understanding of tolerance mechanisms has progressed to the point that tolerance-induction protocols are being tested in humans for organ transplantation. However, a range of scientific, ethical, logistic and commercial issues have arisen, and must be resolved before tolerance induction for human allograft patients can become a reality.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological / immunology*
  • Animals
  • Humans
  • T-Lymphocytes / immunology*
  • Transplantation Immunology*