Abstract
The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Anaphase / physiology
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Animals
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Cdc20 Proteins
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Cdh1 Proteins
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Cell Cycle / physiology*
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Cell Cycle Proteins / metabolism*
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Cell Division
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Fungal Proteins / metabolism
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Mitosis / physiology*
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Models, Biological
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Saccharomyces cerevisiae Proteins*
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Yeasts / cytology
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Yeasts / genetics
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Yeasts / physiology
Substances
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CDC20 protein, S cerevisiae
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Cdc20 Proteins
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Cdh1 Proteins
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Cell Cycle Proteins
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Fungal Proteins
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Saccharomyces cerevisiae Proteins