Inhibitors of glucosylceramide synthase

Methods Enzymol. 2000:311:373-87. doi: 10.1016/s0076-6879(00)11097-3.

Authors

J A Shayman¹, L Lee, A Abe, L Shu

Affiliation

¹ Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109-0676, USA.

PMID: 10563341
DOI: 10.1016/s0076-6879(00)11097-3

No abstract available

MeSH terms

Cell Division / drug effects
Ceramides / biosynthesis
Drug Carriers
Enzyme Inhibitors / pharmacology
Glucosylceramides / biosynthesis*
Glucosyltransferases / antagonists & inhibitors*
Glycosphingolipids / biosynthesis
Morpholines / chemical synthesis
Morpholines / chemistry*
Propanolamines / chemical synthesis
Pyrrolidines / chemical synthesis
Sphingolipids / biosynthesis
Sphingolipids / chemical synthesis
Stereoisomerism

Substances

1-phenyl-2-palmitoylamino-3-morpholino-1-propanol
1-phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol
Ceramides
Drug Carriers
Enzyme Inhibitors
Glucosylceramides
Glycosphingolipids
Morpholines
Propanolamines
Pyrrolidines
Sphingolipids
RV 538
Glucosyltransferases
ceramide glucosyltransferase