Abstract
Fifteen nosocomial cases of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae occurred among 132 neonates in a premature intensive care unit in Hungary in June through November 1998. Fourteen strains were indistinguishable by molecular biological typing and harbored the same single conjugative extended-spectrum beta-lactamase-encoding plasmid that was spontaneously found in a Serratia marcescens strain in the same patient.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Cross Infection / epidemiology*
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Cross Infection / microbiology
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Female
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Humans
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Hungary / epidemiology
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Infant, Newborn
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Infant, Premature
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Infant, Premature, Diseases / epidemiology*
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Infant, Premature, Diseases / microbiology
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Intensive Care Units, Neonatal*
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Klebsiella Infections / epidemiology*
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Klebsiella Infections / microbiology
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / genetics
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Male
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Microbial Sensitivity Tests
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Polymerase Chain Reaction
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Serratia marcescens / enzymology
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Serratia marcescens / genetics
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beta-Lactam Resistance
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beta-Lactamases / biosynthesis
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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beta-lactamase SHV-5
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beta-Lactamases