Molecular epidemiology of a cluster of cases due to Klebsiella pneumoniae producing SHV-5 extended-spectrum beta-lactamase in the premature intensive care unit of a Hungarian hospital

J Clin Microbiol. 1999 Dec;37(12):4167-9. doi: 10.1128/JCM.37.12.4167-4169.1999.

Abstract

Fifteen nosocomial cases of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae occurred among 132 neonates in a premature intensive care unit in Hungary in June through November 1998. Fourteen strains were indistinguishable by molecular biological typing and harbored the same single conjugative extended-spectrum beta-lactamase-encoding plasmid that was spontaneously found in a Serratia marcescens strain in the same patient.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Female
  • Humans
  • Hungary / epidemiology
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / microbiology
  • Intensive Care Units, Neonatal*
  • Klebsiella Infections / epidemiology*
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / enzymology*
  • Klebsiella pneumoniae / genetics
  • Male
  • Microbial Sensitivity Tests
  • Polymerase Chain Reaction
  • Serratia marcescens / enzymology
  • Serratia marcescens / genetics
  • beta-Lactam Resistance
  • beta-Lactamases / biosynthesis
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • beta-lactamase SHV-5
  • beta-Lactamases