Dural sinus thrombosis endovascular therapy

Crit Care Clin. 1999 Oct;15(4):743-53, vi. doi: 10.1016/s0749-0704(05)70085-3.


Dural sinus thrombosis is a relatively rare, but potentially devastating disease. The problem occurs when there is extensive thrombosis of the intracranial dural sinuses, the outflow channels of venous blood from the brain. If recanalization does not occur, venous hypertension can lead to cerebral edema, infarction, and hemorrhage. Treatment of this disease usually involves anticoagulants, but with mixed results. Endovascular approaches using direct infusion of thrombolytic drugs into the occluded sinuses may result in excellent recanalization and improved patient outcomes.

Publication types

  • Review

MeSH terms

  • Cranial Sinuses
  • Dura Mater / blood supply
  • Humans
  • Sinus Thrombosis, Intracranial / diagnosis
  • Sinus Thrombosis, Intracranial / drug therapy*
  • Thrombolytic Therapy / methods*