Endothelium-dependent flow-mediated vasodilation in the postprandial state in type 2 diabetes mellitus

Am J Cardiol. 1999 Nov 15;84(10):1272-4, A9. doi: 10.1016/s0002-9149(99)00548-2.


This study examined the effects of fat- plus sucrose-rich meals on endothelium-dependent flow-mediated vasodilation in diabetic patients. Flow-mediated vasodilation in the postprandial state decreased significantly, and the decrease correlated inversely with the magnitude of postprandial hyperglycemia, suggesting that endothelial function in diabetic patients becomes impaired postprandially.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Endothelium, Vascular / physiopathology*
  • Female
  • Glycated Hemoglobin A / analysis
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Postprandial Period / physiology*
  • Vasodilation / physiology*


  • Glycated Hemoglobin A