Glutathione and its role in cellular functions

Free Radic Biol Med. 1999 Nov;27(9-10):916-21. doi: 10.1016/s0891-5849(99)00177-x.


Glutathione (GSH) is the major cellular thiol participating in cellular redox reactions and thioether formation. This article serves as introduction to the FRBM Forum on glutathione and emphasizes cellular functions: What is GSH? Where does it come from? Where does it go? What does it do? What is new and noteworthy? Research tools, historical remarks, and links to current trends.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Free Radicals / metabolism
  • Glutathione / history
  • Glutathione / metabolism*
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Oxidation-Reduction


  • Free Radicals
  • Glutathione