Is captopril useful in decreasing pleural drainage in children after modified Fontan operation?

Am J Cardiol. 1999 Nov 1;84(9):1109-12, A10. doi: 10.1016/s0002-9149(99)00514-7.


We performed a retrospective cohort study to assess the relation between administration of angiotensin-converting enzyme inhibitors and duration of pleural drainage in the early postoperative period in patients who underwent a modified Fontan operation at our institution from 1990 through 1996. This study failed to show that administration of captopril decreased the duration of pleural drainage in patients after a modified Fontan operation.

MeSH terms

  • Adolescent
  • Angiotensin-Converting Enzyme Inhibitors / administration & dosage*
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects
  • Captopril / administration & dosage*
  • Captopril / adverse effects
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Fontan Procedure*
  • Humans
  • Infant
  • Length of Stay
  • Male
  • Pleural Effusion / drug therapy*
  • Postoperative Complications / drug therapy*
  • Postoperative Period
  • Retrospective Studies
  • Treatment Outcome


  • Angiotensin-Converting Enzyme Inhibitors
  • Captopril