Miriamin, a defensive diterpene from the eggs of a land slug (Arion sp.)

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13620-5. doi: 10.1073/pnas.96.24.13620.

Abstract

The eggs of the land slug Arion sp. contain a diterpene, miriamin, characterized as a polyoxygenated geranylgeraniol derivative. In bioassays with a coccinellid beetle, Harmonia axyridis, miriamin was shown to be potently antifeedant, indicating that the compound plays a protective role in nature. It is suggested that mucilaginous soil-inhabiting organisms, given their intense exposure to pathogens and predators, may be a rich source of chemical defensive agents.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biological Assay
  • Coleoptera
  • Diterpenes / chemistry
  • Diterpenes / pharmacology*
  • Feeding Behavior / drug effects
  • Female
  • Molecular Structure
  • Mollusca / chemistry*
  • Ovum / chemistry

Substances

  • Diterpenes
  • miriamin