The diagnosis and management of solvent-related disorders

Am J Ind Med. 2000 Jan;37(1):44-61. doi: 10.1002/(sici)1097-0274(200001)37:1<44::aid-ajim5>;2-k.


Millions of workers in the United States are recurrently exposed to solvents throughout their working lives. Members of this class of compounds share the ability to dissolve waxes, fats, and oils as their common characteristic. This review offers the health practitioner a practical approach to the diagnosis, management, and prevention of solvent-related disorders that result from exposures to these compounds in the workplace. A description of commonly used solvents is provided, along with a brief review of the literature that documents their acute and chronic effects on health.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Chronic Disease
  • Environmental Monitoring
  • Fats / chemistry
  • Humans
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / diagnosis
  • Occupational Diseases / prevention & control
  • Occupational Diseases / therapy
  • Occupational Exposure
  • Oils / chemistry
  • Solubility
  • Solvents / adverse effects*
  • Solvents / chemistry
  • Solvents / classification
  • Waxes / chemistry


  • Fats
  • Oils
  • Solvents
  • Waxes