Lung cancer associated with pulmonary bulla. case report and review of literature

Respiration. 1999 Nov-Dec;66(6):555-8. doi: 10.1159/000029436.


A few reports have suggested the possible association between lung cancer and bullous disease. We report a surgical case of lung adenocarcinoma located in close proximity to pulmonary bullae. A 48-year-old nonsmoker, asymptomatic male was found to have a pulmonary tumor mass and giant bulla in the right lung. Thoracotomy identified a tumor arising from a firm, scarred and contracted area close to the bulla wall. Based on this report and review of other cases in the literature, we emphasize the need for physicians to be aware of the potential development of lung cancer in patients with pulmonary bulla.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / surgery
  • Blister / complications
  • Blister / diagnosis*
  • Blister / surgery
  • Fatal Outcome
  • Follow-Up Studies
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / surgery
  • Male
  • Middle Aged
  • Pneumonectomy
  • Pulmonary Emphysema / diagnosis
  • Pulmonary Emphysema / etiology
  • Pulmonary Emphysema / surgery