Endometrial polyps during menopause: characterization and significance

Acta Obstet Gynecol Scand. 1999 Nov;78(10):883-6.


Background: To characterize postmenopausal women with endometrial polyps and to evaluate their significance.

Methods: The study population included all consecutive postmenopausal patients with a diagnosis of endometrial polyp, treated at our center over a two-year period. Demographic, medical and gynecological data were assessed with regard to the endometrial histologic findings.

Results: Of the 146 eligible patients, 15 had endometrial hyperplasia (four with atypia); there were no cases of endometrial carcinoma. The 20 patients (13.7%) using hormone replacement therapy had a significantly higher rate of endometrial hyperplasia than non-hormone users (p<0.006). No differences were observed among the endometrial histological categories for any of the presenting symptoms and signs, ultrasonographic findings, or medical histories.

Conclusions: Postmenopausal endometrial polyp is a common, mostly benign entity. However, the relatively high rate of concomitant endometrial hyperplasia, especially in patients receiving hormone replacement therapy, dictates a thorough histological evaluation in all cases.

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Endometrial Neoplasms / diagnosis*
  • Endometrial Neoplasms / pathology
  • Endometrium / pathology
  • Female
  • Humans
  • Hyperplasia
  • Middle Aged
  • Polyps / diagnosis*
  • Polyps / pathology
  • Postmenopause
  • Retrospective Studies