Hepatocellular carcinoma: treatment with transcatheter arterial chemoembolization

Eur J Radiol. 1999 Oct;32(1):86-9. doi: 10.1016/s0720-048x(99)00117-5.


This article presents a review of the literature regarding the use of transcatheter arterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma (HCC). There have been two different approaches to the treatment: (a) percutaneous tumor ablation methods which can be divided into injectable and thermal methods; percutaneous ethanol injection (PEI) is the most widely used method, and (b) TACE. PEI is the treatment of choice for single HCCs smaller or equal to 3 cm in size. For patients with large HCCs combined TACE and PEI is probably the most effective nonsurgical treatment. In the presence of multiple HCC nodules, TACE remains the treatment of choice.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Carcinoma, Hepatocellular / therapy*
  • Chemoembolization, Therapeutic*
  • Doxorubicin / administration & dosage
  • Ethanol / administration & dosage
  • Female
  • Humans
  • Laser Coagulation
  • Liver Neoplasms / therapy*
  • Male
  • Mitomycin / administration & dosage


  • Ethanol
  • Mitomycin
  • Doxorubicin