Iron and activated oxygen species in biology: the basic chemistry

Biometals. 1999 Sep;12(3):195-9. doi: 10.1023/a:1009252919854.


This paper briefly presents a critical review concerning the chemical reactions involved when superoxide or hydrogen peroxide meet iron complexes. The data commented on are required for a correct interpretation of the chemical processes which play a paramount role in the biological activation of dioxygen and arise in normal metabolism as well as in pathological processes.

Publication types

  • Review

MeSH terms

  • Iron / chemistry*
  • Iron / metabolism*
  • Oxidation-Reduction
  • Reactive Oxygen Species / metabolism*


  • Reactive Oxygen Species
  • Iron