Homeopathic prophylaxis of headaches and migraine? A systematic review

J Pain Symptom Manage. 1999 Nov;18(5):353-7. doi: 10.1016/s0885-3924(99)00095-0.


Homeopathy is often advocated as a prophylaxis of migraine and headaches. The aim of this systematic review was to evaluate the clinical trials, testing the efficacy of homeopathy for these indications. Independent computerized literature searches were carried out in 4 databases. Only randomized, placebo-controlled trials were included. Four such studies were found. Their methodological quality was variable but, on average, satisfactory. One study suggested that homeopathic remedies were effective. The other, methodologically stronger trials did not support this notion. It is concluded that the trial data available to date do not suggest that homeopathy is effective in the prophylaxis of migraine or headache beyond a placebo effect.

Publication types

  • Systematic Review

MeSH terms

  • Evaluation Studies as Topic
  • Homeopathy* / standards
  • Humans
  • Migraine Disorders* / prevention & control
  • Preventive Medicine* / methods
  • Preventive Medicine* / standards
  • Randomized Controlled Trials as Topic