Topical N-acetylcysteine for lamellar ichthyosis

Lancet. 1999 Nov 27;354(9193):1880. doi: 10.1016/S0140-6736(99)04245-2.

Abstract

The antioxidant N-acetylcysteine has an antiproliferative effect on a culture of human keratinocytes. We report a patient with lamellar ichthyosis satisfactorily treated with topical N-acetylcysteine.

Publication types

  • Case Reports
  • Clinical Trial
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Acetylcysteine / pharmacology
  • Acetylcysteine / therapeutic use*
  • Administration, Topical
  • Adult
  • Cells, Cultured
  • Emulsions
  • Female
  • Free Radical Scavengers / pharmacology
  • Free Radical Scavengers / therapeutic use*
  • Humans
  • Ichthyosis, Lamellar / drug therapy*
  • In Vitro Techniques
  • Keratinocytes / drug effects

Substances

  • Emulsions
  • Free Radical Scavengers
  • Acetylcysteine