Abstract
Sixteen cases of colitis developing within twenty-one days of antibiotic therapy are reported. There was a wide range of disease severity. Lincomycin and Clindamycin were implicated in twelve. The colitis was of two pathological patterns pseudomembranous colitis and "non-specific" colitis. There is a relative sparing of the rectum in some cases making the diagnosis more difficult on sigmoidoscopy.
MeSH terms
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Adult
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Aged
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Anti-Bacterial Agents / adverse effects*
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Clindamycin / adverse effects
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Colitis / chemically induced*
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Colitis / pathology
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Colitis / therapy
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Colon / pathology
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Diarrhea / chemically induced*
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Diarrhea / therapy
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Enterocolitis, Pseudomembranous / chemically induced
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Enterocolitis, Pseudomembranous / pathology
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Female
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Humans
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Intestinal Mucosa / pathology
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Lincomycin / adverse effects
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Male
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Middle Aged
Substances
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Anti-Bacterial Agents
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Clindamycin
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Lincomycin