Therapeutic strategies for allergic diseases

Nature. 1999 Nov 25;402(6760 Suppl):B31-8. doi: 10.1038/35037026.


Many drugs are now in development for the treatment of atopic diseases, including asthma, allergic rhinitis and atopic dermatitis. These treatments are based on improvements in existing therapies or on a better understanding of the cellular and molecular mechanisms involved in atopic diseases. Although most attention has been focused on asthma, treatments that inhibit the atopic disease process would have application to all atopic diseases, as they often coincide. Most of the many new therapies in development are aimed at inhibiting components of the allergic inflammatory response, but in the future there are real possibilities for the development of preventative and even curative treatments.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Animals
  • Anti-Allergic Agents / therapeutic use*
  • Anti-Asthmatic Agents / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Asthma / drug therapy
  • Cytokines / drug effects
  • Genetic Therapy
  • Humans
  • Hypersensitivity / drug therapy*
  • Hypersensitivity / prevention & control
  • Immunotherapy
  • Inflammation Mediators / antagonists & inhibitors


  • Adrenal Cortex Hormones
  • Anti-Allergic Agents
  • Anti-Asthmatic Agents
  • Anti-Inflammatory Agents
  • Cytokines
  • Inflammation Mediators