Increased coverage of protein families with the blocks database servers

Nucleic Acids Res. 2000 Jan 1;28(1):228-30. doi: 10.1093/nar/28.1.228.


The Blocks Database WWW ( ) and Email ( ) servers provide tools to search DNA and protein queries against the Blocks+ Database of multiple alignments, which represent conserved protein regions. Blocks+ nearly doubles the number of protein families included in the database by adding families from the Pfam-A, ProDom and Domo databases to those from PROSITE and PRINTS. Other new features include improved Block Searcher statistics, searching with NCBI's IMPALA program and 3D display of blocks on PDB structures.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Databases, Factual*
  • Information Storage and Retrieval
  • Internet
  • Molecular Sequence Data
  • Proteins / chemistry*
  • Sequence Homology, Amino Acid


  • Proteins