Endobronchial metastasis from osteosarcoma of bone: treatment with intraluminal radiotherapy

Chest. 1999 Dec;116(6):1811-4. doi: 10.1378/chest.116.6.1811.


Lung parenchymal metastases are common manifestations in patients with osteosarcoma; however, spread to the major airway itself is extremely rare. We present a young man who had been previously treated with surgical resection following preoperative chemotherapy and immediate postsurgical adjuvant chemotherapy for proximal tibial osteosarcoma. He developed metastasis to the major airways. The patient was treated with intraluminal radiotherapy (ILT) for the endobronchial metastasis. This is the first report of an endobronchial osteosarcoma that was treated with ILT with a complete endoscopic response. ILT provided excellent palliation in this particular case.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / therapy
  • Bronchial Neoplasms / pathology
  • Bronchial Neoplasms / radiotherapy*
  • Bronchial Neoplasms / secondary*
  • Fatal Outcome
  • Humans
  • Male
  • Osteosarcoma / pathology
  • Osteosarcoma / radiotherapy*
  • Osteosarcoma / secondary*
  • Palliative Care
  • Tibia*