Use of minimally modified antisense oligonucleotides for specific inhibition of gene expression

Methods Enzymol. 2000;313:268-84. doi: 10.1016/s0076-6879(00)13017-4.
No abstract available

MeSH terms

  • Animals
  • Base Sequence
  • Biological Transport
  • Cell Line
  • Chromatography, High Pressure Liquid / methods
  • Drug Design
  • Gene Expression Regulation / drug effects*
  • Genes, myc / drug effects
  • Oligodeoxyribonucleotides, Antisense / chemical synthesis*
  • Oligodeoxyribonucleotides, Antisense / chemistry
  • Oligodeoxyribonucleotides, Antisense / pharmacology*
  • Spectrometry, Mass, Secondary Ion / methods
  • Structure-Activity Relationship
  • Thionucleotides

Substances

  • Oligodeoxyribonucleotides, Antisense
  • Thionucleotides