Sputum induction to improve the diagnostic yield in patients with suspected pulmonary tuberculosis

Int J Tuberc Lung Dis. 1999 Dec;3(12):1137-9.


Objective: To evaluate the utility of sputum induction in the large-scale tuberculosis control program.

Methods: Prospective study on sputum induction for improving the diagnostic yield of pulmonary tuberculosis, and estimation of the direct costs for sputum induction.

Results: Of 1,648 tuberculosis suspects with poor or absent sputum production, induced sputum was smear-positive in 558 patients (353 previously smear-negative, 97 inadequate sputum and 108 unproductive). The direct cost per induced sputum was US $0.37.

Conclusion: Sputum induction is an effective, low-cost, and simple technique for improving the smear-positive case detection rate in a tuberculosis control program.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Costs and Cost Analysis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium tuberculosis / isolation & purification*
  • Prospective Studies
  • Specimen Handling / economics
  • Sputum / microbiology*
  • Tuberculosis, Pulmonary / economics
  • Tuberculosis, Pulmonary / prevention & control*