Human retroviral sequences associated with extracellular particles in autoimmune diseases: epiphenomenon or possible role in aetiopathogenesis?

Microbes Infect. 1999 Apr;1(4):309-22. doi: 10.1016/s1286-4579(99)80027-6.

Abstract

Publications describing retroviral sequences associated with extracellular particles in Sjögren's syndrome or systemic lupus erythematosus, multiple sclerosis, and type I diabetes present novel arguments and raise complex questions about eventual relationships between retroviruses and autoimmunity. They are presented and discussed in the present review, preceded by an overview of the biology of retroviral elements.

Publication types

  • Review

MeSH terms

  • Animals
  • Arthritis, Rheumatoid / virology
  • Autoimmune Diseases / virology*
  • Diabetes Mellitus, Type 1 / virology
  • Endogenous Retroviruses / classification
  • Endogenous Retroviruses / genetics
  • Endogenous Retroviruses / isolation & purification
  • Endogenous Retroviruses / physiology*
  • Evolution, Molecular
  • Genome, Viral
  • Humans
  • Lupus Erythematosus, Systemic / virology
  • Multiple Sclerosis / virology
  • Retroelements
  • Retroviridae / classification
  • Retroviridae / genetics
  • Retroviridae / isolation & purification
  • Retroviridae / physiology*
  • Sjogren's Syndrome / virology
  • Virion / genetics
  • Virion / physiology

Substances

  • Retroelements