Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS

Antimicrob Agents Chemother. 2000 Jan;44(1):167-8. doi: 10.1128/AAC.44.1.167-168.2000.


A patient with AIDS and chronic diarrhea caused by Enterocytozoon bieneusi was successfully treated with nitazoxanide, producing a complete clinical and parasitological response, while off of antiviral therapy. This suggests that nitazoxanide may be effective in treating microsporidiosis caused by E. bieneusi, a disease for which there is no established treatment.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Animals
  • Antiprotozoal Agents / therapeutic use*
  • Diarrhea / drug therapy*
  • Humans
  • Male
  • Microsporida*
  • Microsporidiosis / drug therapy*
  • Nitro Compounds
  • Thiazoles / therapeutic use*


  • Antiprotozoal Agents
  • Nitro Compounds
  • Thiazoles
  • nitazoxanide