Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema

Clin Exp Rheumatol. Nov-Dec 1999;17(6):741-4.

Abstract

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a syndrome that may be associated with many conditions, including malignancy. Three further cases of paraneoplastic RS3PE are described and the literature is reviewed. Paraneoplastic RS3PE is more frequently associated with solid tumors, in particular adenocarcinoma. The two clinical characteristics suggestive of paraneoplastic RS3PE are systemic sign/symptoms and the poor response to corticosteroid therapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / diagnosis
  • Aged
  • Edema / blood
  • Edema / diagnosis*
  • Edema / drug therapy
  • Fatal Outcome
  • Foot / pathology*
  • Foot Diseases / blood
  • Foot Diseases / diagnosis*
  • Foot Diseases / drug therapy
  • Hand / pathology*
  • Humans
  • Lung Neoplasms / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Paraneoplastic Syndromes / blood
  • Paraneoplastic Syndromes / diagnosis*
  • Paraneoplastic Syndromes / drug therapy
  • Prednisone / therapeutic use
  • Serologic Tests
  • Sigmoid Neoplasms / diagnosis
  • Synovitis / blood
  • Synovitis / diagnosis*
  • Synovitis / drug therapy

Substances

  • Prednisone