Effect of fat and carbohydrate consumption on endothelial function

Lancet. 1999 Dec;354(9196):2134. doi: 10.1016/s0140-6736(99)03374-7.

Abstract

Consumption of a meal high in monounsaturated fat was associated with acute impairment of endothelial function when compared with a carbohydrate-rich meal. Such a divergent response in endothelial function may be important in the modulation of vascular function in health and disease.

Publication types

  • Clinical Trial
  • Comparative Study
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Brachial Artery / diagnostic imaging
  • Cross-Over Studies
  • Dietary Carbohydrates / administration & dosage
  • Dietary Carbohydrates / pharmacology*
  • Dietary Fats / administration & dosage
  • Dietary Fats / pharmacology*
  • Double-Blind Method
  • Endothelium, Vascular / drug effects*
  • Fasting / metabolism
  • Humans
  • Male
  • Regional Blood Flow / drug effects
  • Triglycerides / blood
  • Ultrasonography

Substances

  • Dietary Carbohydrates
  • Dietary Fats
  • Triglycerides