[Sildenafil citrate (viagra) treatment in patients with diabetes mellitus]

Ter Arkh. 1999;71(10):78-80.
[Article in Russian]

Abstract

Aim: To evaluate different dosages of vasoactive drug viagra in patients with erectile dysfunction suffering from diabetes mellitus (DM) type I and II.

Materials and methods: Viagra in doses 25, 50 and 100 mg was given to 30 DM patients with different forms of erectile dysfunction.

Results: The response was obtained in 70.3% of cases. The highest effect was achieved with the dose 100 mg (the response rate 68.5% of patients). The dose 50 mg was effective in 31.5%, 25 mg in 0% of patients. Most nonresponders had low testosterone levels in the blood.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • 3',5'-Cyclic-GMP Phosphodiesterases / antagonists & inhibitors*
  • Adult
  • Aged
  • Biomarkers / blood
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / complications*
  • Dose-Response Relationship, Drug
  • Erectile Dysfunction / blood
  • Erectile Dysfunction / complications
  • Erectile Dysfunction / drug therapy*
  • Humans
  • Male
  • Middle Aged
  • Phosphodiesterase Inhibitors / administration & dosage*
  • Phosphodiesterase Inhibitors / therapeutic use
  • Piperazines / administration & dosage*
  • Piperazines / therapeutic use
  • Purines
  • Sildenafil Citrate
  • Sulfones
  • Testosterone / blood
  • Treatment Outcome

Substances

  • Biomarkers
  • Blood Glucose
  • Phosphodiesterase Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Testosterone
  • Sildenafil Citrate
  • 3',5'-Cyclic-GMP Phosphodiesterases