Pulmonary tuberculosis sequelae with chronic respiratory failure is a clinical picture that is often mentioned, but seldom separately described, in connection with noninvasive ventilation in the case of acute or chronic respiratory failure. We report on the functional data and the ventilation of 26 patients. The patient group is characterized by great chronological latency between the start of pulmonary tuberculosis and the development of respiratory illness. Acute or chronic respiratory failure with this clinical entity should be treated in the form of noninvasive positive pressure ventilation.