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. 1999 Dec 16;402(6763):769-77.
doi: 10.1038/47134.

Sequence and Analysis of Chromosome 4 of the Plant Arabidopsis Thaliana

K Mayer  1 C SchüllerR WambuttG MurphyG VolckaertT PohlA DüsterhöftW StiekemaK D EntianN TerrynB HarrisW AnsorgeP BrandtL GrivellM RiegerM WeichselgartnerV de SimoneB ObermaierR MacheM MüllerM KreisM DelsenyP PuigdomenechM WatsonT SchmidtheiniB ReichertD PortatelleM Perez-AlonsoM BoutryI BancroftP VosJ HoheiselW ZimmermannH WedlerP RidleyS A LanghamB McCullaghL BilhamJ RobbenJ Van der SchuerenB GrymonprezY J ChuangF VandenbusscheM BraekenI WeltjensM VoetI BastiaensR AertE DefoorT WeitzeneggerG BotheU RamspergerH HilbertM BraunE HolzerA BrandtS PetersM van StaverenW DirskeP MooijmanR Klein LankhorstM RoseJ HaufP KötterS BerneiserS HempelM FeldpauschS LamberthH Van den DaeleA De KeyserC BuysshaertJ GielenR VillarroelR De ClercqM Van MontaguJ RogersA CroninM QuailS Bray-AllenL ClarkJ DoggettS HallM KayN LennardK McLayR MayesA PettettM A RajandreamM LyneV BenesS RechmannD BorkovaH BlöckerM ScharfeM GrimmT H LöhnertS DoseM de HaanA MaarseM SchäferS Müller-AuerC GabelM FuchsB FartmannK GranderathD DaunerA HerzlS NeumannA ArgiriouD VitaleR LiguoriE PiravandiO MassenetF QuigleyG ClabauldA MündleinR FelberS SchnablR HillerW SchmidtA LecharnyS AubourgF ChefdorR CookeC BergerA MontfortE CasacubertaT GibbonsN WeberM VandenbolM BarguesJ TerolA TorresA Perez-PerezB PurnelleE BentS JohnsonD TaconT JesseL HeijnenS SchwarzP SchollerS HeberP FrancsC BielkeD FrishmanD HaaseK LemckeH W MewesS StockerP ZaccariaM BevanR K WilsonM de la BastideK HabermannL ParnellN DedhiaL GnojK SchutzE HuangL SpiegelM SehkonJ MurrayP SheetM CordesJ Abu-ThreidehT StonekingJ KalickiT GravesG HarmonJ EdwardsP LatreilleL CourtneyJ CloudA AbbottK ScottD JohnsonP MinxD BentleyB FultonN MillerT GrecoK KempJ KramerL FultonE MardisM DanteK PepinL HillierJ NelsonJ SpiethE RyanS AndrewsC GeiselD LaymanH DuJ AliA BerghoffK JonesK DroneM CottonC JoshuB AntonoiuM ZidanicC StrongH SunB LamarC YordanP MaJ ZhongR PrestonD VilM ShekherA MateroR ShahI K SwabyA O'ShaughnessyM RodriguezJ HoffmannS TillS GranatN ShohdyA HasegawaA HameedM LodhiA JohnsonE ChenM MarraR MartienssenW R McCombie
Affiliations

Sequence and Analysis of Chromosome 4 of the Plant Arabidopsis Thaliana

K Mayer et al. Nature. .

Abstract

The higher plant Arabidopsis thaliana (Arabidopsis) is an important model for identifying plant genes and determining their function. To assist biological investigations and to define chromosome structure, a coordinated effort to sequence the Arabidopsis genome was initiated in late 1996. Here we report one of the first milestones of this project, the sequence of chromosome 4. Analysis of 17.38 megabases of unique sequence, representing about 17% of the genome, reveals 3,744 protein coding genes, 81 transfer RNAs and numerous repeat elements. Heterochromatic regions surrounding the putative centromere, which has not yet been completely sequenced, are characterized by an increased frequency of a variety of repeats, new repeats, reduced recombination, lowered gene density and lowered gene expression. Roughly 60% of the predicted protein-coding genes have been functionally characterized on the basis of their homology to known genes. Many genes encode predicted proteins that are homologous to human and Caenorhabditis elegans proteins.

Comment in

  • Today we have naming of parts.
    Meyerowitz EM. Meyerowitz EM. Nature. 1999 Dec 16;402(6763):731-2. doi: 10.1038/45398. Nature. 1999. PMID: 10617191 No abstract available.

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