Light-induced fluorescence endoscopy of the gastrointestinal tract

Gastrointest Endosc Clin N Am. 2000 Jan;10(1):37-69, vi.


The early detection of dysplasia and superficial malignant lesions of the gastrointestinal tract is of significant clinical importance. Recent advances in fluorescence-based endoscopic imaging and spectroscopy of the gastrointestinal tract may offer alternative means of detecting and identifying premalignant and malignant lesions that were otherwise occult or nonspecific on conventional white-light endoscopy. The purpose of this article is to present a general overview of the current developments and possible clinical roles of light-induced fluorescence endoscopy as an adjunct to routine diagnostic endoscopy to enhance screening and surveillance for premalignant and malignant gastrointestinal lesions.

Publication types

  • Review

MeSH terms

  • Endoscopy, Gastrointestinal / methods*
  • Fluorescence
  • Fluorescent Dyes*
  • Humans
  • Intestinal Neoplasms / diagnosis
  • Intestinal Neoplasms / prevention & control
  • Intestines / pathology
  • Light*
  • Mass Screening
  • Precancerous Conditions / diagnosis
  • Precancerous Conditions / prevention & control
  • Spectrometry, Fluorescence
  • Stomach / pathology
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / prevention & control


  • Fluorescent Dyes