Angiomyolipoma of the large intestine: report of a case

Mod Pathol. 1999 Dec;12(12):1132-6.

Abstract

A case of an angiomyolipoma of the large intestine occurring in a 55-year-old man without evidence of tuberous sclerosis is reported. Endoscopically, the lesion resembled a sessile adenomatous polyp. The tumor measured 1 cm. Histologic examination revealed a lesion composed predominantly of spindle and epithelioid cells with significant nuclear atypia. Mitoses were rare. The tumor was strongly positive for HMB-45, CD68, vimentin, desmin, and smooth muscle actin. Rare scattered cells reacted with CD34. No residual tumor was found in the resected colon.

Publication types

  • Case Reports

MeSH terms

  • Actins / metabolism
  • Anastomosis, Surgical
  • Angiomyolipoma / metabolism
  • Angiomyolipoma / pathology*
  • Angiomyolipoma / surgery
  • Antigens, CD / metabolism
  • Antigens, Differentiation, Myelomonocytic / metabolism
  • Antigens, Neoplasm / metabolism
  • Colectomy
  • Colonic Neoplasms / metabolism
  • Colonic Neoplasms / pathology*
  • Colonic Neoplasms / surgery
  • Desmin / metabolism
  • Humans
  • Male
  • Melanoma-Specific Antigens
  • Middle Aged
  • Neoplasm Proteins / metabolism
  • Vimentin / metabolism

Substances

  • Actins
  • Antigens, CD
  • Antigens, Differentiation, Myelomonocytic
  • Antigens, Neoplasm
  • CD68 antigen, human
  • Desmin
  • Melanoma-Specific Antigens
  • Neoplasm Proteins
  • Vimentin