Cardiac involvement in Becker's muscular dystrophy, necessitating heart transplantation, 6 years before apparent skeletal muscle involvement

Neuromuscul Disord. 1999 Dec;9(8):598-600. doi: 10.1016/s0960-8966(99)00045-0.

Abstract

In Becker's muscular dystrophy cardiac abnormalities usually occur after onset of neuromuscular symptoms. We describe a Becker muscular dystrophy patient in whom chronic heart failure, necessitating cardiac transplantation, was the initial manifestation. Neuromuscular symptoms occurred not earlier than 6 years after the initial cardiac symptoms and 5 years after heart transplantation. In conclusion, severe heart failure due to dilated cardiomyopathy may be the initial manifestation of Becker's muscular dystrophy and may predate neuromuscular symptoms for years.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cardiac Output, Low / etiology
  • Cardiomyopathy, Dilated / complications
  • Cardiomyopathy, Dilated / surgery*
  • Chronic Disease
  • Heart Transplantation*
  • Humans
  • Male
  • Muscle, Skeletal / physiopathology*
  • Muscular Dystrophy, Duchenne / complications*
  • Muscular Dystrophy, Duchenne / physiopathology*
  • Time Factors